|
KMID : 0191120100250081231
|
|
Journal of Korean Medical Science
2010 Volume.25 No. 8 p.1231 ~ p.1233
|
|
|
A Case of Anaphylaxis to Oral Minocycline
|
|
Jang Ji-Woong
Bae Yun-Jeong
Kim Yong-Giun
Jin Young-Joo
Park Kyung-Sun
Cho You-Sook
Moon Hee-Bom
Kim Tae-Bum
|
|
|
Abstract
|
|
|
|
Minocycline is a semisynthetic tetracycline derivative that is often used in the treatment of acne vulgaris. To date, there has been only one case report of anaphylaxis to minocycline. We report here a case of anaphylaxis to oral minocycline. A 56-yr-old woman visited our hospital after three episodes of recurrent anaphylaxis. We performed an oral challenge test, the standard method for diagnosing drug allergies, with minocycline, one of the drugs she had taken previously. She developed urticaria, angioedema, nausea, vomiting, hypotension, and dyspnea within 4 min and was treated with intramuscular epinephrine, intravenous antihistamine and systemic corticosteroid. However, she presented similar symptoms at 50 min and at 110 min. In prescribing oral minocycline, physicians should consider the possibility of serious adverse reactions, such as anaphylaxis.
|
|
|
KEYWORD
|
|
|
Anaphylaxis, Minocycline, Oral Challenge Test, Allergy
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
    
|
|